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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIG1
All Species:
13.33
Human Site:
T218
Identified Species:
26.67
UniProt:
P18858
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18858
NP_000225.1
919
101736
T218
L
Q
E
E
E
E
Q
T
K
P
P
R
R
A
P
Chimpanzee
Pan troglodytes
XP_524321
919
101662
T218
L
Q
E
E
E
E
Q
T
K
P
P
R
R
A
P
Rhesus Macaque
Macaca mulatta
XP_001111346
919
101454
T218
L
Q
E
E
E
E
Q
T
K
P
P
R
S
A
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P37913
916
102271
Q216
L
K
P
Q
E
E
E
Q
S
K
P
P
A
R
G
Rat
Rattus norvegicus
Q9JHY8
918
102463
Q218
Q
K
P
Q
E
E
E
Q
S
K
P
P
A
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
P51892
1070
120215
K351
S
D
E
E
P
Q
K
K
A
D
S
A
K
P
V
Zebra Danio
Brachydanio rerio
NP_001119860
1058
118776
T346
V
V
K
K
E
K
D
T
D
G
G
S
A
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1H4
747
84700
H112
D
P
S
A
D
S
Y
H
P
L
K
N
A
Y
W
Honey Bee
Apis mellifera
XP_392286
861
97795
D211
K
S
S
N
H
S
Y
D
P
S
I
S
N
Y
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180844
967
108403
T247
N
K
K
E
K
E
K
T
E
E
K
K
E
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42572
790
87722
K155
K
S
K
I
G
L
L
K
K
K
P
N
D
F
D
Baker's Yeast
Sacchar. cerevisiae
P04819
755
84810
P120
S
S
G
V
A
D
S
P
Q
Q
S
Q
R
L
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
98.2
N.A.
N.A.
84
81.3
N.A.
N.A.
N.A.
56.9
56.1
N.A.
44
46
N.A.
48.5
Protein Similarity:
100
99.4
98.8
N.A.
N.A.
89.3
87.8
N.A.
N.A.
N.A.
71.1
68.6
N.A.
60.2
65.7
N.A.
66.2
P-Site Identity:
100
100
93.3
N.A.
N.A.
26.6
20
N.A.
N.A.
N.A.
13.3
13.3
N.A.
0
0
N.A.
20
P-Site Similarity:
100
100
93.3
N.A.
N.A.
46.6
40
N.A.
N.A.
N.A.
33.3
40
N.A.
6.6
0
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.3
36
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.3
53.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
0
0
0
9
0
0
9
34
25
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
0
0
9
9
9
9
9
9
0
0
9
0
9
% D
% Glu:
0
0
34
42
50
50
17
0
9
9
0
0
9
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
9
0
9
0
0
0
0
9
9
0
0
0
17
% G
% His:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
17
25
25
9
9
9
17
17
34
25
17
9
9
9
9
% K
% Leu:
34
0
0
0
0
9
9
0
0
9
0
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
9
0
0
0
0
0
0
0
17
9
0
9
% N
% Pro:
0
9
17
0
9
0
0
9
17
25
50
17
0
9
25
% P
% Gln:
9
25
0
17
0
9
25
17
9
9
0
9
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
25
25
17
0
% R
% Ser:
17
25
17
0
0
17
9
0
17
9
17
17
9
0
0
% S
% Thr:
0
0
0
0
0
0
0
42
0
0
0
0
0
0
0
% T
% Val:
9
9
0
9
0
0
0
0
0
0
0
0
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
17
0
0
0
0
0
0
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _